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Widespread demonstrations in mid-1987 led to new elections and a calmer political situation, although students called for greater efforts for reunification of the north and south, and electoons of the large number of American troops continued. North-South talks in 1990 produced an agreement in principle on reunification in the near future.

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Small companies have a role, often then selling the rights to larger companies that have the resources to run the clinical trials. This made for the beginning of the era in pharmacology, as pure chemicals, instead of crude extracts. Examples of drug compounds isolated from crude preparations are morphine, the agent in opium, and digoxin. Organic chemistry also led to the synthesis of many of the natural products isolated from biological sources, historically substances, whether crude extracts or purified chemicals were screened for biological activity without knowledge of the biological target. Only after a substance was identified was an effort made to identify the target. This approach is known as classical pharmacology, forward pharmacology, or phenotypic drug discovery, later, small molecules were synthesized to specifically target a known physiologicalpathological pathway, rather than adopt the mass screening of banks of stored compounds.

With illegally revoking their hospital. privileges after the doctors invested in. a competing specialty facility. appears that some of the next battles.]