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SVR12 in GT 1, TN adults without cirrhosis who had pre-treatment HCV RNA lt;6 million IUmL. 8 weeks of HARVONI can be considered in adult GT 1, TN patients without cirrhosis who have pre-treatment HCV RNA lt;6 million IUmL 1 12 weeks of HARVONI is the recommended duration for GT 1 TN adults without cirrhosis or with compensated cirrhosis 1 ION-3 common adverse events ([AEs] ‚5) among patients taking HARVONI for 8 weeks: fatigue (21), headache (14), nausea (7), diarrhea (7), insomnia (5); discontinuations due to AEs (0) 5 In HARVONI clinical trials, the most common adverse reactions (ge;10, all grades) were fatigue, headache, and asthenia 1 The pooled real-world analysis did not provide safety results HCV-TARGET most common (ge;10) AEs (among patients taking 8, 12, or 24 weeks of HARVONI): fatigue (23), headache (21); discontinuations due to AEs (3) 3. INDICATION. HARVONI is indicated for the treatment of adults with chronic hepatitis C virus (HCV) genotype (GT) 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis. HARVONI is used with ribavirin in GT 1 adults with decompensated cirrhosis and in GT 1 or 4 adult liver transplant recipients without cirrhosis or with compensated cirrhosis. Overall Real-world.

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