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20 of subjects had compensated cirrhosis Median age: 57 years (range: 24 to 75) 65 were male; 35 were female 81 were White; 18 were Black; 9 were Hispanic or Latino Mean BMI was 28 kgm 2 (range: 19 to 50 kgm 2 ) 89 had baseline HCV RNA levels ge; 800,000 IUmL 79 had HCV GT 1a 88 had IL28B non-CC alleles (CT or TT) 53 failed prior therapy with an HCV protease inhibitor Peg-IFN RBV regimen (62 were relapsebreakthrough; 38 were nonresponder) 47 of subjects failed prior therapy with Peg-IFN RBV (49 were relapsebreakthrough; 51 were nonresponder) INDICATION. HARVONI is indicated for the treatment of adults with chronic hepatitis C virus (HCV) genotype (GT) 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis. HARVONI is used with ribavirin in GT 1 adults with decompensated cirrhosis and in GT 1 or 4 adult liver transplant recipients without cirrhosis or with compensated cirrhosis.

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